منابع مشابه
Osteoarticular Changes in Acromegaly
Acromegaly is caused by hypersecretion of growth hormone (GH) and consequently of insulin-like growth factor-I (IGF-1) due to pituitary tumor. Other causes, such as increased growth-hormone releasing hormone (GHRH) production, ectopic GHRH production, and ectopic GH secretion, are rare. Growth hormone and IGF-1 play a role in the regulation of bone metabolism, but accurate effect of growth horm...
متن کاملOsteoarticular changes and synovial biopsy findings in Wilson's disease.
Wilson's disease (hepatolenticular degeneration) is an uncommon recessively inherited disease, in which various osteoarticular changes have been described (Finby and Beam, 1958; Rosenoer and Michell, 1959; Walshe, 1962; Boudin, Pepin, and Hubault, 1964; Charbonnel, Vercelletto, LeMouroux, Besan9on, and Feve, 1965; Mehta and Shinde, 1965; Cavallino and Grossman, 1968; Mindelzun, Elkin, Scheinber...
متن کاملOsteoarticular brucellosis in children.
The findings in 40 children (24 female, 16 male) with osteoarticular complications of brucellosis are presented. Raw milk was the main source of infection. Most patients had acute onset of fever, arthralgia, and myalgia. Arthritis was the presenting symptom in all patients, of whom two also had osteomyelitis. Arthritis was monoarticular in 28 (70%) of 40 cases with predilection for large weight...
متن کاملObstructive sleep apnoea in acromegaly: the role of craniofacial changes.
Obstructive sleep apnoea (OSA) is due to craniofacial changes and acromegaly. The question addressed by this study was whether growth hormone (GH) induced craniofacial changes might explain persisting OSA despite endocrine inactivity in acromegaly. Nineteen patients treated for acromegaly were examined cephalometrically for craniofacial changes and polysomnographically for OSA. Twelve patients ...
متن کاملCardiovascular changes in patients with acromegaly assessed by CMR
Results In patients with acromegaly left ventricular (LV) mass index (LVMi) was increased (65.7 vs. 45.8 g/m2, p=0.0021) and was observed in both females (58.8 v. 40.9 g/m2, p=0.0028) and males (71.1 vs. 56.7 g/m2, p=0.0286) compared to matched controls. The LVMi did not correlate with the serum insulin growth factor (IGF) activity (r=0.099, p=0.745) or age (r=-0.08, p=0.175). Patients with acr...
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ژورنال
عنوان ژورنال: International Journal of Endocrinology
سال: 2012
ISSN: 1687-8337,1687-8345
DOI: 10.1155/2012/839282